Differential Diagnosis > Distribution > Acral > Hands and/or Feet > Palms and/or Soles > Keratoderma

Keratoderma

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diffuse palmar keratoderma (tylosis) is associated with carcinoma of the esophagus in a cluster of familial UK cases, but only requires investigation if there is a family history of this association

 

tripe palms

Dowling-Meara EBS??

 

hmtoggle_plus1acquired:
•keratoderma climactericum

 

hmtoggle_plus1acquired focal:
•corns, calluses
•porokeratosis plantaris
•digitate keratosis spines like those of an old-fashioned music box

 

hmtoggle_plus1hereditary types:
•punctate palmoplantar keratosis the main symptom is pruritis
•hidrotic ectodermal dysplasia

 

hmtoggle_plus1hereditary transgradiens:

 

hmtoggle_plus1associated palmoplantar keratoderma:
•pachyonychia congenita
•dyskeratosis congenita
•PRP

 

PPK Bullets:

•Unna-Thost                AD
•Vorner variant        AD (histology – EHK)
•Mal de Meleda        AR (transgradiens)
•Papillon-Lefevre        AR (transgradiens and loss of teeth)