| GI problem: | Associated Dermatologic Diagnosis: |
| IBD | PG, erythema nodosum, aphthae |
| Hirschsprung disease | (<5%) in Waardenberg's syndrome |
| colon cancer | Gardner's syndrome |
| hamartomatous polyps | Peutz-Jeghers syndrome |
| celiac sprue (gluten sensitive enteropathy) | dermatitis herpetiformis |
| pyloric atresia | junctional EB (when alpha 6 beta 4 integrin = antigen) |
| constipation | phenolphthalein laxatives – fixed drug |
| primary biliary cirrhosis | pruritis, diffuse hyperpigmentation |
| hemochromotosis | bronze diabetes, may exacerbate PCT (by increased iron) |
| • | blue rubber bleb nevus syndrome |
| • | mastocytosis (increased histamine --> decreases gastric pH --> ulcers) ?? |
|
| • | Gardner’s
~ 100% malignant adenocarcinoma by age 30 |
| • | Muir-Torre colon cancer (most common underlying malignancy) |
|
Dermatologic Changes in Chronic Liver Disease
|
