Basic Science / Structures > Immune System > Cells > Eosinophils > Eosinophils and disease

Eosinophils and disease

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Eosinophilic fasciitis
Eosinophilic cellulitis (Wells syndrome)
Eosinophilic Myalgia syndrome
Eosinophilic folliculitis
Erythema toxicum neonatorum
Sweets syndrome
Granuloma Faciale
Hypereosinophilic syndrome
Churg-Strauss syndrome
angiolymphoid hyperplasia with eoisinophilia
Kimuras disease
eosinophilic granuloma
papuloerythroderma of Ofuji

 

hmtoggle_plus1Peripheral eosinophilia ddx:

NAACP

Neoplasm
Allergic reaction
Addisons disease (glucocorticoids suppress eosinophils or cause margination???)
CVD
Parasites

 

 

Histologic ddx:

 

hmtoggle_plus1Interstitial eosinophils (~ dermal hypersensitivity):
refers to the presence of eosinophils between the collagen bundles away from vessels (though perivascular eosinophils are also present)
urticarial stages of BP, herpes gesationis
arthropod bites/ parasites
drug reactions
PUPPPS
urticaria
Wells syndrome
hypereosinophilic syndrome

 

 

hmtoggle_plus1Eosinophilic spongiosis:
(i.e. the eosinophils are in the epidermis)
mnemonic = HAAPPI
herpes gestationis (urticarial lesions)
arthropod bite reaction
allergic contact dermatitis
pemphigoid (urticarial lesions;  BP and cicatricial)
pemphigus vulgaris and foliaceus
IP, “Id”