Differential Diagnosis > Morphology > Reaction Patterns Expanded > Poikiloderma > Poikiloderma Genodermatoses

ruled out by Normal Height

 Top  Previous  Next

PEARL:  can rule out most of the poikilodermatous genodermatoses, if patient has normal height:

 

poikiloderma / Dwarfism Genodermatoses:

1.Bloom syndrome
2.Cockayne syndrome
3.Rothmund-Thomson syndrome (short stature)

 

all three:

•photosensitive
•autosomal recessive
•DNA helicase

 

 

poikiloderma in a child, also consider:

•collagen vascular disease (neonatal LE, dermatomyositis)
•+/- dyskeratosis congenita (X-linked recessive)