By Disease Name > Papuloerythroderma (of Ofuji)

Papuloerythroderma (of Ofuji)

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•a rare disorder most commonly found in Japan
•characterized by pruritic flat-topped papules that spare the skin folds = the “deck chair sign”
•considered a form of erythroderma in the elderly by some and a paraneoplastic syndrome by others
•frequently there is an associated blood eosinophilia
•histology – dense lymphohistiocytic infiltrate, eosinophils in papillary dermis
•not enough cases have been reported to determine a true association with malignancies