palpable purpura = vasculitis
• | palpable because of inflammation |
• | end stage of "vascular reaction pattern" (wheal = early stage) |
• | septic = distal, sparse (small # of lesions), and asymmetric |
• | hypersensitivity = symmetric bilateral lower extremities |
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Septic Vasculitis
• | distal, sparse (small # of lesions), and asymmetric |
• | if become generalized, think of superimposed DIC |
• | embolization of organisms |
• | pseudomonas (e.g. ecthyma gangrenosum) |
• | subacute bacterial endocarditis |
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Hypersensitivity Vasculitis
• | symmetric bilateral lower extremities; palpable purpura |
• | etiologies: drug, group A beta-hemolytic strep (antecedent URI), collagen vascular disease |
• | clinical ddx: benign pigmented purpura, scurvy, Kaposi's sarcoma |
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