Leukoplakia
• | a clinical term; used to describe a wide range of non-specific white lesions |
• | causes: smoking (most common), chronic irritation from carious teeth or malaligned dentures |
• | histology: ranges from mild epidermal thickening to varying degrees of dysplasia or carcinoma (SCC ~ 17%) |
• | clinical does not correlate well with histology, therefore biopsy all (simply follow if benign histology) |
• | ddx: candidiasis, LP, habitual cheek biting, white sponge nevus, secondary syphilis, oral hairy leukoplakia |
Miscellaneous:
Leukemia cutis: (AML) (M4 and M5 are more likely to involve skin and gums?) (i.e. monocytic (vs. myelogenous) are more likely to produce oral lesions)
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