| • | AKA lymphocytic infiltrate of the skin (LIS) |
| • | a chronic, benign, T-cell infiltrative disorder, usually of exposed skin |
clinical:
| • | red, tumid nodules, usually on facial skin |
| • | annular and arciform lesions are common |
| • | the lesions may involute spontaneously but more commonly, are persistent |
histology:
| • | superficial and deep perivascular infiltrate of small mature lymphocytes |
| • | lymphoid follicles are absent |
ddx:
| • | tumid LE – abundant dermal mucin and subtle alterations at the DE interface (scaling and scarring; though some view Jessner’s as a chronic variant of DLE) |
| • | REM – reticulated clinical appearance, favors trunk rather than head and neck; shows bipolar fibroblast |
| • | PMLE – papillary dermal edema (absent in Jessner’s) |
| • | Lymphocytoma cutis – nodular or diffuse, dermal lymphoid infiltrates that are much denser than the predominantly perivascular infiltrate in Jessner’s (also Jessner’s lacks reactive B-cell follicles; because it is a T-cell disease) |
| • | small lymphocytic lymphoma/ leukemia – usually a monoclonal B-cell process; there is peripheral lymphocytosis in the leukemic form of the disease |
| • | deep figurate erythema (e.g. erythema chronicum migrans) |
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