Basic Science / Structures > Immune System > Hypersensitivity

Hypersensitivity

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type I (immediate)

mediator release:

•cutaneous --> hives
•systemic --> bronchospasm, laryngeal edema, N/V/D, hypotension
•mediators = histamine, serotonin, leukotrienes, prostaglandins

 

type II (cytotoxic)

•ex. bullous pemphigoid

type III (immune complex)

•ex. vasculitis

type IV (delayed hypersensitivity;  cell-mediated)

•ex. allergic contact dermatitis