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TNF (tumor necrosis factor):
| • | a major cause of septic shock accompanying severe gram-negative infections |
INTERFERONS:
| • | two different families of genes |
| • | these two types of IFN proteins are unrelated to each other structurally and their major functions are also different |
| • | however, all IFN’s inhibit the replication of diverse viruses and they share other actions |
Type I IFN:
| • | the IFN alpha/beta “superfamily” |
Type II IFN:
|