Differential Diagnosis > Morphology > Color > Hyperpigmentation > Hyperpigmented Macules

Hyperpigmented Macules

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hmtoggle_plus1Peutz-Jeghers disease
•pigmented macules (especially peri-oral)
•hamartomatous GI polyps
•autosomal dominant

 

hmtoggle_plus1Laugier-Hunziker syndrome:
•hyperpigmented macules on lips and oral mucosa
•longitudinal melanonychia

 

hmtoggle_plus1Cronkhite-Canada syndrome:
•melanotic macules on fingers (not oral)
•GI polyposis
•Japanese

 

 

                                                       


Oral/lip hyperpigmented macules

GI polyposis

fingers/nails

Peutz-Jeghers dz

X

X

(hyperpigmented macules may fade with time)

 

Cronkite-Canada sx        

 

X

(hyperpigmented macules on fingers)

Laugier-Hunziker sx

X

 

longitudinal melanonychia