Marker:
|
Cells:
|
Description:
|
|
|
|
CD2
|
T cells
|
adhesion molecule, present on most mature T cells, often lost
in transformation
|
|
|
|
CD3
|
T cells
|
transduces activation signal from antigen receptor
|
|
|
|
CD4
|
helper T cells
|
binds to class II MHC
|
|
|
|
CD7
|
|
|
|
|
|
CD8
|
suppressor T cells
|
binds to class I MHC
|
|
|
|
CD 25
|
activated T cells
|
IL-2 receptor (Tac), induced by HTLV-1)
|
|
|
|
CD30
|
activated T cells
|
Ki-1 marker, found in anaplastic T-cell lymphomas, LyP
|
|
|
|
CD45
|
leukocyte common
|
isoforms of CD45 appear with T-cell activation
|
|
|
|
CD45RO
|
memory cells
|
irreversibly formed after T-cell activation
|
|
|
|
CLA-1
|
skin associated lymphocytes
|
homing receptor that bind ELAM-1
|
|
|
|
TCR
|
T cells
|
two varieties: alpha-beta and gamma-delta (these are proteins that bind specific antigens)
|
|
|
|
V-beta
|
T cells
|
variable region specific antibodies (approx. 45 different regions)
|