By Disease Name > Trichorrhexis Nodosa
Trichorrhexis Nodosa
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•
grossly
–
multiple tiny white “beads” are seen on the distal hair shaft
•
under microscope
–
cortical fibers splayed out at both ends
•
incidental finding
secondary to trauma
•
also seen in
arginosuccinic aciduria
(urea cycle defect
–
die as infants or are severely mentally retarded)