By Disease Name > Transient Neonatal Pustular Melanosis

Transient Neonatal Pustular Melanosis

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•   often present at birth (even in utero)
•benign; uncommon disorder seen primarily in black infants
•TRANSIENT:  quickly ruptures and leaves a typical collarette
•NEONATAL PUSTULAR:  the original lesion is a vesicopustule very superficial (can wipe off), which may be present at birth (even in utero)
•MELANOSIS: brownish pigmented macules develop at the site of each resolving pustule
•trunk, palms, and soles; asymptomatic and self-limiting
•scraping (Tzank) of pustule à PMN’s (= polymorphic nucleocytes: AKA neutrophils)
•ddx: erythema toxicum neonatorum, viral infections, IP, staph impetigo

 

mnemonic: neonatal pustular melanosis – npm à PMN’s on tzank smear