By Disease Name > Sjogrens syndrome

Sjogrens syndrome

Top  Previous  Next
•>90% women
•skin - LCV (patients with cutaneous vasculitis have a high prevelance of peripheral or CNS vasculitis)
•labs - rheumatoid factor positive (usually), Ro (80%)
•definitive diagnosis:  labial salivary gland biopsy from lower lip
•ddx:  sarcoid, amyloid, lymphoma, HIV

 

2 out of 3:

1.xeropthalmia
2.xerostomia
3.an associated autoimmune, rheumatic, or lymphoproliferative disorder patients are predisposed to lymphoreticular malignancies (e.g. non-Hodgkins)