By Disease Name > Lupus > Neonatal LE

Neonatal Lupus

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•a rare disease characterized by the transplacental passage from the mother to the fetus of autoantibodies (in particular Ro and La)
•syndrome characterized by presence of one or more of the following:
•cutaneous lesions resembling adult SCLE
•usually disappear in weeks to months
•no scarring or hyperpigmentation;  but persistent telangiectasia
•congenital heart block
•complete,and irreversible in half of NLE cases
•cholestatic liver disease
•thrombocytopenia