• | occurs most commonly in the urinary and GI tract, rarely is the skin affected (although if present, it is usually the vulva or perianal areas) |
• | skin lesions are variable – fluctuant abscess, draining sinuses |
• | lesions are the result of faulty phagocytosis of bacteria by macrophages |
• | Michaelis-Gutman bodies – are seen in histiocytes and are thought to be phagolysosomes |
• | E. coli and Staph Aureus are cultured from tissue (with E. coli being most common) |
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