Basic Science / Structures > Immune System > Major Histocompatibility Complex Molecules

Major Histocompatibility Complex Molecules

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•Class I (HLA-A,B, and C) --> presents antigen to CD8+ T-cells
•Class II (HLA-D) --> presents antigen to CD4+ T-cells
•related: CD1 molecules – bind non-peptide antigens à for presentation to a different subgroup of T-cells