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(most common to less common)
| • | hydroxyurea can cause severe painful leg ulcers (discontinuation heals) |
see also Wound Healing
Venous stasis ulcers:
| • | location – medial ankle or lower calf |
| • | symptoms – painless or mild |
| • | characteristics – red base of granulation tissue; surrounding hyperpigmentation; depth: shallow; warm feet |
Arterial ulcers (due to large vessels):
| • | location – usually toes or foot; lateral aspect of ankle |
| • | characteristics – black or gray base; no granulation tissue; depth: deep; cold feet |
| • | cause – arteriosclerosis obliterans, thromboangiitis obliterans |
Neurotropic ulcers:
| • | location – over metatarsal arch, heel, toes |
| • | characteristics – deep and surrounded by callus |
| • | cause – diabetes and other neuropathies |
Hypertensive ulcers:
| • | lateral and posterior calf; severe pain |
| • | black eschar surrounded by purpura |
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