By Disease Name > Dowling-Degos Disease

Dowling-Degos Disease

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•AKA reticulate pigmented anomaly of the flexures
•AKA dark dot disease
•autosomal dominant; presents in adult life
•axilla and groin most often
•vs. Kitimuras:  acral
•vs. Habers disease:  rosacea of the face in addition
•“classic ddx”:  AN vs. Gougerot-Carteaud vs. Dowling-Degos dz

 

hmtoggle_plus1Reticulate Epidermal Hypermelanosis
•Dowling-Degos Disease
•Dyskeratosis Congenita
•Kitamura’s

 

histology:

•diagnostic;  a distinctive form of acanthosis, characterized by an irregular elongation of the thin, branching, rete ridges (described as “antlers”;  look like adenoidal seborrheic keratosis) with a concentration of melanin at the tips
•melanocyte count normal
•histology distinguishes from AN and axillary freckling of neurofibromatosis