| • | ddx: psoriasis, chronic eczema (including tinea), superficial BCC, seborrheic keratosis |
| • | histology: atypical cells throughout entire thickness of epidermis, and involve epidermal appendages, especially hair follicles (vs. AK) |
| • | classic immunohistochemistry panel: Paget’s vs. superficial spreading melanoma vs. Bowen's (see EMPD for detailed immunohistochemistry) |
| • | appears exclusively under the foreskin of the uncircumcised penis |
| • | treatment of choice = 5-FU cream vs. aldara |
| • | recurrences are unlikely because hair follicles that serve as foci for recurrence are absent on the penile mucosa |
|
|
