By Disease Name > Angiolymphoid Hyperplasia with Eosinophilia

Angiolymphoid Hyperplasia with Eosinophilia

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the five L's extended ddx:

 

•AKA epithelioid hemangioma
•Kimura’s disease:  may be a distinct variant with deeper seated lesions that have no initial overlying skin lesions
•an apparently benign locally proliferating lesion composed of vascular channels with a surrounding infiltrate of lymphocytes and eosinophils
•more common in Japan
•etiology unknown, but antigenic stimulation following insect bites has been postulated

 

clinical:

•commonly young adults (age 30-50) who present with a cluster of small, translucent nodules around the ear or the hairline
•may also involve the oral mucosa
•spontaneous regression in the majority of cases
•peripheral blood eosinophilia may be present (especially in Kimura’s variant)
•treatment:  observe 3-6 months and await regression vs. intralesional cortisone injection or pulsed dye laser