By Disease Name > Acrodermatitis Continua

Acrodermatitis Continua

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•AKA Hallapeau’s disease
•now classified as a form of acropustular psoriasis

 

clinical:

•most often begins at the tips of one or two fingers (or less often toes)
•nail folds are affected early
•small pustules burst leaving an erythematous shiny area in which new pustules develop
•as the disease extends proximally the affected area shows either glossy erythema or a crusted, keratotic, and fissured surface with newly formed pustules underneath

 

course:

•chronic course, with a tendency of the lesions to spread proximally (hence the name “continua” – it ‘continues’ to spread proximally;  and it ‘continues’ to persist – i.e. spontaneous improvement is rare)
•may remain confined to original site, sometimes up to several years
•the development of pustules at other sites, or even the eruption of generalized pustular psoriasis, supports the idea that acrodermatitis continua is a variant of psoriasis

 

ddx:

•(early stage ddx) = acute paronychia
•PPP or pustular dishydrotic eczema
•atrophy and loss of nails do not occur in these diseases
•the distal localization and the tendency of the pustules to become confluent, forming denuded, erythematous or crusted lesions distinguishes acrodermatitis continua
•contact dermatitis with secondary infection – has less clearly defined margins, runs a different clinical course, and lacks the persistence

 

treatment:

•no specific drug brings lasting remission;  i.e. always relapse after drug is withdrawn (like psoriasis)
•potent topical glucocorticoids (under occlusion) are useful in blocking pustulation
•PUVA (i.e. treatment options similar to PPP and psoriasis)
•try tetracycline 500PO QID  and topical steroids under occlusion.