| • | 2-12 days after chemotherapy |
| • | daunorubicin, cytarabine (ara-C), hydroxyurea, 5-fluorouracil, methotrexate |
| • | toxic process (necrosis of keratinocytes) |
therapy:
| • | pyridoxine, local therapy, topical steroids, cool compresses |
| • | (cyclosporine increases pain, IV prednisone increase infection) |
ddx:
| • | difficult to differentiate from GVHD in bone marrow recipient |
| • | but totally different treatment; GVHD treatment includes systemic steroids and cyclosporine |
| • | acrodynia (mercury poisoning) |
| • | in children: Kawasaki (check perineum) |
see Toxic Erythema of Chemotherapy
|